Europe PMC
Verdict: NotableSingle-cell atlas of transcriptomic vulnerability across brain disorders
Neurodegenerative and neuropsychiatric diseases impose a considerable societal and public health burden.
- Cites 5
Biology
Genomes, cells, brains, and the tools that read and write them.
Edition No. 2
Updated UTC
Top stories
1. Traversing the solution space of neural networks with Hessian Null Space Continuation
On a single task, deep networks can learn many solutions, depending on their optimizer, training data, architecture, and hyperparameters.
█████░░░░░4.72. A ReAct Agentic AI System for Natural Language Querying and Statistical Analysis of The Cancer Genome Atlas Clinical Data
The Cancer Genome Atlas (TCGA) holds clinical data for over 11,000 patients across 33 cancer types, but access is hard because of complex file structures, heterogeneous formats, and the need for programming.
█████░░░░░4.63. Universal scaling relationships of marine and terrestrial photoautotrophs with differing developmental trajectories
Backgrounds and Aims: Partitioning of biomass to various organs is fundamental to growth and survival strategies of plant species, with broad-scale ecological implications from competition to carbon flux of ecosystems.
█████░░░░░4.6
More top stories
- bioRxivby Porter, Borkowski
vep-rs: high-throughput Rust variant annotation with population-scale concordance to Ensembl VEP
Summary: Ensembl VEP is the de facto reference for variant consequence annotation, but its Perl implementation limits throughput, and the open reimplementation benchmarked here is ....
No.04Verdict: NotableScore█████░░░░░4.6 - bioRxivby ADJI, Assiri, Assi +2
Planted origin of shade trees: a robust determinant of cocoa yield among smallholder farmers in Cote d'Ivoire
CONTEXT: While the agroeconomic literature on the determinants of cocoa yield among West African smallholders is abundant, it remains dominated by descriptive studies or work conducted at ....
No.05Verdict: NotableScore█████░░░░░4.6 - bioRxivby Yang, Lubkowitz, Marth +6
DS5: An Open-Source Framework for Standardized High-Throughput Drug Screening Data Storage, Analysis, and Drug Prioritization
Background.
No.06Verdict: NotableScore█████░░░░░4.6
Briefs
- Europe PMC
Single-nucleus atlas of cell-type specific genetic regulation in the human brain
█████░░░░░4.6 - arXiv
Flattening the Connectome Spectrum: A Spectral Filter for FC Induces a Pretraining Target for fMRI Encoders
█████░░░░░4.5 - bioRxiv
MIMOSA: Guiding De Novo Antibody Design with Natural Interaction Fingerprints
█████░░░░░4.5 - arXiv
LEMON-ZEST: Evolution-Informed Tokenization for Efficient Protein Language Modeling
█████░░░░░4.5 - bioRxiv
Identifying, phasing, and structurally annotating sex chromosomes for genome assemblies using CBS-tools
████░░░░░░4.5 - bioRxiv
EpiZoo: a DNA sequence-aware foundation model for cross-species single-cell epigenomics
████░░░░░░4.4 - bioRxiv
Accurate and scalable demultiplexing of single-cell RNA sequencing using BEACON
████░░░░░░4.4 - bioRxiv
RNASeek: A Cross-Phyla Generative Foundation Model for Multipurpose RNA Modeling and Reinforcement Learning-Based Design
████░░░░░░4.4