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A General-Purpose Dual-Path Interaction Framework for Multi-View Medical Image Segmentation: Alleviating Data Volume Dependency in Small-Sample Regimes

The performance of medical image segmentation depends on a large amount of annotated data, and most segmentation models experience a significant drop in performance in low-sample-size scenarios.

By Wang, Cui, Wang +10

Score████░░░░░░3.5

Key numbers

  • 60% of the data achieve

Caveats

  • Preprint; not yet peer reviewed.

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Abstract

The performance of medical image segmentation depends on a large amount of annotated data, and most segmentation models experience a significant drop in performance in low-sample-size scenarios. Existing semi-supervised and weakly supervised methods rely on specific network architectures, while traditional multi-view-assisted segmentation methods require strictly paired samples, which limits their clinical applications. To address these issues, we propose DPIF, a general-purpose plug-and-play dual-path interaction framework compatible with arbitrary encoder-decoder segmentation networks, which leverages cross-view anatomical complementarity to reduce annotation reliance. DPIF first performs Sinkhorn optimal transport-based cross-view distribution alignment to establish global semantic correspondence without sample-level pairing. It then adopts conditional mutual information-guided feature decoupling to enable bidirectional knowledge transfer only within the shared semantic space, suppressing view-specific noise. Finally, persistent homology-based topological regularization encodes anatomical invariants as unsupervised priors to mitigate overfitting. Experiments were conducted using 24 baseline models on a private multicenter echocardiography dataset and two public datasets. The results show that DPIF-enhanced models outperform single-view baseline models when trained on comparable amounts of data. Notably, most dual-path variants trained on 40% - 60% of the data achieve performance comparable to that of single-view models trained on the full dataset. This demonstrates that DPIF provides a general-purpose and scalable solution for data-scarce multi-view medical image segmentation problems.

Shuhuan Wang, Yuanyuan Cui, Pengju Wang, Huimin Guo, Ling Yue, Yin Gu, Yanchao Zhang, Wei Feng, Yunhe Liu, Wei Qian, Mingjun Xu, Shuang Liu, He Ma

The editor's rubric

Heuristic review

Leverage4 / 5
A general-purpose tool used across several fields (Adam, ResNet, LoRA, next-generation sequencing).
24% of this desk’s rubric
Magnitude3 / 5
Large gain: roughly 2x, or a clear new state of the art on a hard, unsaturated problem.
18% of this desk’s rubric
Evidence3 / 5
Solid: multiple benchmarks or cohorts, ablations, fair baselines, released code or data.
14% of this desk’s rubric
Novelty2 / 5
A new combination of known ideas.
16% of this desk’s rubric
Trajectory3 / 5
A clear path to scale.
18% of this desk’s rubric
Stakes2 / 5
Benefits a professional community (practitioners, clinicians, engineers).
10% of this desk’s rubric

Editor’s rationale

Heuristic triage from title and abstract text only, not a reading of the paper. Cues found: method (we propose); breadth (general-purpose, many tasks); gains (outperforms); design (multicenter); verification (multiple benchmarks); scale (scalable); stakes (global scale).

How the score was computed

rank-2026-10-18

Score████░░░░░░3.5

Score = 10 × (65% × adjusted merit / 10 + 25% × attention + 10% × freshness)

Desks place stronger verdicts first, then use this score to order work within the same verdict.

Merit
6.0 / 10
Weighted rubric, evidence-gated.
Adjusted merit
4.9 / 10
Shrunk toward the desk prior by editor confidence (46%).
Attention
0%
Citations, upvotes, points, mentions.
Freshness
36%
Half-life decay since publication.

No attention signals recorded yet.

The record

  • Reviewed by heuristic-v10 on Oct 25, 2026, 13:49 UTC. Paper type: method.
  • Categories: cs.CV
  • Not yet placed in an edition.