Humanity’s List

Research with real-world weight.

Vol. I · No. 27Updated UTC
Ranked by formula

MedicineEurope PMC

Verdict: Major

Retatrutide Once Weekly for Treatment of Obstructive Sleep Apnea

Retatrutide, an investigational triple agonist of glucose-dependent insulinotropic polypeptide, glucagon-like peptide 1, and glucagon receptors, may be useful for treating obstructive sleep apnea (OSA).

By Grunstein, Somers, Azarbarzin +10The New England journal of medicine

Score█████░░░░░4.7

Top stories

  1. MedicineEurope PMC

    1. Individualized Cardiac Index-Guided Hemodynamic Therapy in High-Risk Patients Undergoing Elective Major Abdominal Surgery: The PELICAN Randomized Clinical Trial

    It remains unclear if intraoperative hemodynamic therapy should be guided by cardiac index.

    Verdict: Major████░░░░░░4.4
  2. BiologybioRxiv

    2. PROTFIG: one-command, publication-quality biomolecular figures

    Molecular structures contain rich information about biomolecular interactions, but translating this information into clear, scientifically informative figures remains a largely manual process.

    Verdict: Notable█████░░░░░4.6
  3. BiologybioRxiv

    3. TRUEDA overturns replicated, decontaminated low-biomass disease-microbe associations and clinical decisions, recovers true pathogens and outperforms every decontamination method

    Most low-biomass disease-microbe associations measure biomass, not disease.

    Verdict: Notable█████░░░░░4.5
  4. AIarXiv

    5. Harness Scaling for Generalizable Agentic Reinforcement Learning

    Verdict: Notable████░░░░░░4.3
  5. PhysicsarXiv

    6. Synthetic 2D magnetic turbulence with controlled island structuring

    Verdict: Notable████░░░░░░4.3

Sections

bioRxiv

Population-scale drug target and variant prioritization with Varformer

Human genetic variation is a powerful driver of therapeutic target prioritization, yet current models struggle to aggregate variable numbers of variants per gene and are bottlenecked by the scarcity of validated targets.

By Wenteler, Neduva, Genes & Health Research Team +3

Verdict: Notable█████░░░░░4.5

Europe PMC

Magic state cultivation on a superconducting quantum processor

Fault-tolerant quantum computing requires a universal gate set, but the necessary non-Clifford gates represent a significant resource cost for most quantum error correction architectures.

By Rosenfeld, Gidney, Roberts +197Science (New York, N.Y.)

Verdict: Notable█████░░░░░5.0
  • Cites 52

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