Europe PMC
Verdict: NotableSingle-cell atlas of transcriptomic vulnerability across brain disorders
Neurodegenerative and neuropsychiatric diseases impose a considerable societal and public health burden.
- Cites 5
Biology
Genomes, cells, brains, and the tools that read and write them.
Edition No. 1
Updated UTC
From the archiveYou are reading the September 29, 2026 edition. Read the latest
Top stories
1. A ReAct Agentic AI System for Natural Language Querying and Statistical Analysis of The Cancer Genome Atlas Clinical Data
The Cancer Genome Atlas (TCGA) holds clinical data for over 11,000 patients across 33 cancer types, but access is hard because of complex file structures, heterogeneous formats, and the need for programming.
█████░░░░░4.72. Universal scaling relationships of marine and terrestrial photoautotrophs with differing developmental trajectories
Backgrounds and Aims: Partitioning of biomass to various organs is fundamental to growth and survival strategies of plant species, with broad-scale ecological implications from competition to carbon flux of ecosystems.
█████░░░░░4.73. vep-rs: high-throughput Rust variant annotation with population-scale concordance to Ensembl VEP
Summary: Ensembl VEP is the de facto reference for variant consequence annotation, but its Perl implementation limits throughput, and the open reimplementation benchmarked here is validated on a set too small to bound…
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More top stories
- bioRxivby ADJI, Assiri, Assi +2
Planted origin of shade trees: a robust determinant of cocoa yield among smallholder farmers in Cote d'Ivoire
CONTEXT: While the agroeconomic literature on the determinants of cocoa yield among West African smallholders is abundant, it remains dominated by descriptive studies or work conducted at ....
No.04Verdict: NotableScore█████░░░░░4.6 - bioRxivby Yang, Lubkowitz, Marth +6
DS5: An Open-Source Framework for Standardized High-Throughput Drug Screening Data Storage, Analysis, and Drug Prioritization
Background.
No.05Verdict: NotableScore█████░░░░░4.6 - Europe PMCby Zeng, Yang, Prashant N +14
Single-nucleus atlas of cell-type specific genetic regulation in the human brain
Genetic risk variants for common diseases are predominantly located in non-coding regulatory regions and modulate gene expression.
No.06Verdict: NotableScore█████░░░░░4.6
Briefs
- bioRxiv
MIMOSA: Guiding De Novo Antibody Design with Natural Interaction Fingerprints
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Identifying, phasing, and structurally annotating sex chromosomes for genome assemblies using CBS-tools
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EpiZoo: a DNA sequence-aware foundation model for cross-species single-cell epigenomics
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RNASeek: A Cross-Phyla Generative Foundation Model for Multipurpose RNA Modeling and Reinforcement Learning-Based Design
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Luxar: Gaussian splatting for microscopy and scalable interactive web visualisation of multidimensional scientific data
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Biologically grounded cell profiling across microscopy modalities
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Fitting dynamics is not identifying causal edges: a white-box masked ODE benchmark for trans-omics digital twins of drug action mechanisms
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PanVasc Research for AI assisted evidence analysis in panvascular intervention
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