Trials, therapies, and evidence that changes care.
Europe PMC
Verdict: MajorBackground RIPK1, a protein regulating inflammatory signalling and cell death, is implicated in amyotrophic lateral sclerosis (ALS) pathophysiology.
Objective In prespecified analyses, the treatment effect for major adverse cardiovascular event (MACE) of tirzepatide compared with imputed placebo was estimated using SURPASS-Cardiovascular Outcomes Trial…
Purpose We aimed to investigate the prognostic and predictive value of tumor-infiltrating lymphocytes (TIL) for adjuvant immunotherapy in high-risk early triple-negative breast cancer (TNBC).
Background The clinical effects of dual antiplatelet therapy de-escalation after acute myocardial infarction may differ by age.
Abstract Classic Hodgkin lymphoma (cHL) associated with Epstein-Barr virus (EBV) positive status as well as nonnodular sclerosis (non-NS) histologic subtypes has demonstrated poorer ....
Background WHO grade 2 atypical meningioma is a primary brain tumour with a high risk of recurrence even after complete surgical resection.
Background Orforglipron is an oral, non-peptide GLP-1 receptor agonist.