medRxiv
Verdict: NotableImmune Training with BCG therapy in Diabetes: Outcomes of a Phase 2 randomized clinical trial
BCG is a well recognized old generic drug that can mold the human immune system through Immune Training.
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Medicine
Trials, therapies, and evidence that changes care.
Edition No. 16
Updated UTC
Top stories
1. Effectiveness of a mHealth nutrition and lifestyle intervention (mHENAL) in reducing Cardiovascular Disease Risk in Sri Lankan adults: A Randomized Control Trial
Cardiovascular diseases (CVD) are the leading cause of global mortality, responsible for 17.8 million deaths and 423 million prevalent cases annually.
█████░░░░░5.02. Efficacy of Repeated-Dose Albendazole/ Mebendazole Regimens for Soil-Transmitted Helminth Infections in Paediatric Population: A Systematic Review and Meta-Analysis
Preventive chemotherapy via single-dose benzimidazoles remains the core strategy for soil-transmitted helminth (STH) control.
█████░░░░░4.83. Efficacy of Disease-Modifying Treatments in Transthyretin Amyloid Cardiomyopathy: A Systematic Review and Meta-Analysis of Five Phase III Randomized Controlled Trials
Several disease-modifying agents for transthyretin amyloid cardiomyopathy (ATTR-CM) have been investigated, but differences in trial design and background stabilizer use complicate interpretation of their…
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More top stories
- medRxivby AMBROSE, Kabangi, Mwaka
Predictors of malaria prevention practices among HIV-positive patients attending an antiretroviral therapy clinic in Kampala, Uganda: a cross-sectional study
Malaria and HIV remain major causes of illness in sub-Saharan Africa, accounting for 94% of the global malaria burden and over two-thirds of the global HIV burden.
No.04Verdict: NotableScore█████░░░░░4.8 - medRxivby Sui, Campos, Kwon +8
Long-read sequencing and benchmarking of saliva against blood for genomic variant detection in autism
Autism is highly heritable, yet many cases remain genetically unsolved even after short-read sequencing (SRS).
No.05Verdict: NotableScore█████░░░░░4.8 - Europe PMCby Sun, Chen, Tang +27
Hypofractionated versus conventional fractionated postmastectomy radiotherapy for patients with high-risk breast cancer (CHN HYPOPMRT): 10-year outcomes from a randomised, non-inferiority, open-label, phase 3 trial
Hypofractionated radiotherapy is an established alternative to conventional fractionation for breast cancer, but long-term evidence after mastectomy with regional nodal irradiation is ....
No.06Verdict: MajorScore█████░░░░░4.7
Briefs
- Europe PMC
Felzartamab plus lenalidomide-dexamethasone versus lenalidomide-dexamethasone for relapsed or refractory multiple myeloma: an open-label, parallel-controlled, randomised, phase 3 trial
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Survodutide Once Weekly in Adults with Obesity and Type 2 Diabetes
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Quantifying Systematic Bias in Observational Causal Estimates Using Negative Controls: The Bias Attribution Fraction
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Anticholinergic Co-Medication Burden Does Not Predict Cardiac Toxicity in Adolescent Diphenhydramine Exposure: A Pharmacovigilance Study of the FDA Adverse Event Monitoring System
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Digital wellbeing in the social media era: dual pathway analysis of emotional and behavioural distress indicators and public health utility
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Pulsed Field Versus Radiofrequency Ablation For Repeat Ablation of Atrial Fibrillation: Evaluation of Outcomes
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Giredestrant plus Everolimus in Advanced Breast Cancer
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Personalised normative cardiac phenotyping reveals clinically relevant heterogeneity in cardiac shape and outcome risk
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