Section

Biology

Genomes, cells, brains, and the tools that read and write them.

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Edition No. 9
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Top stories

  1. 1. Linear Fitness Subspace in Protein Language Models Enables Sample-Efficient Directed Evolution

    Model-guided directed evolution seeks to identify high-fitness protein variants under limited oracle budgets.

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  2. 2. Comparative analysis of mitochondrial proteomes across the tree of life

    Mitochondria arose from the endosymbiosis of a bacterium with an archaea-related host cell about 2 billion years ago.

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  3. 3. A Unified Unsupervised Framework for Genome-Wide Association Studies in Heterogeneous Populations

    Genome-wide association studies (GWAS) have greatly advanced the discovery of genetic variants underlying complex traits and diseases.

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