Genomes, cells, brains, and the tools that read and write them.
bioRxiv
Verdict: NotablePeptide toxicity remains a major bottleneck in drug development, as small sequence variations can drastically alter cytotoxic profiles.
The Practical Molecular Optimization (PMO) benchmark standardized evaluation in molecular optimization, but it is built on simple property-based oracles that do not capture structure-based drug design.
Normative models chart how brain measures vary across the lifespan, expressing each individual as a deviation from a healthy reference.
When nanoparticles enter biological environments, their surfaces are rapidly coated by proteins, forming a protein corona that governs their biological identity and downstream responses.
Antibody developability is determined by multiple physicochemical properties, and the relevance of individual properties varies among experimental assays.
Medical multimodal reasoning models are typically trained on teacher-generated rationales, discarding the valid reasoning in students' own failed trajectories, while general-domain ....