Genomes, cells, brains, and the tools that read and write them.
bioRxiv
Verdict: NotableWhen nanoparticles enter biological environments, their surfaces are rapidly coated by proteins, forming a protein corona that governs their biological identity and downstream responses.
Antibody developability is determined by multiple physicochemical properties, and the relevance of individual properties varies among experimental assays.
Learned protein representations contribute to the broad utility of pretrained protein language models (PLMs), often enhanced by task-specific fine-tuning where parameter-efficient techniques are imperative due to large…
Integrative macromolecular docking pipelines generate thousands of candidate structural decoys, relying on downstream pairwise ensemble analysis, including Root-Mean-Square Deviation ....
Accurate reconstruction of tumor cell phylogenies is crucial for understanding cancer evolutionary dynamics, inferring intra-tumor heterogeneity, and designing effective and personalized ....
Spatial profiling is moving from method development into a central platform for biological discovery and clinical translation, but analyzing such complex data has become the bottleneck of ....