arXiv
Verdict: NotableDe novo design of monoclonal and bispecific antibodies with OFAntibody
Recent advances in generative protein design have enabled de novo antibody generation with explicit target and epitope conditioning.
Score█████░░░░░4.5
Biology
Genomes, cells, brains, and the tools that read and write them.
Edition No. 10
Updated UTC
Top stories
1. A Unified Unsupervised Framework for Genome-Wide Association Studies in Heterogeneous Populations
Genome-wide association studies (GWAS) have greatly advanced the discovery of genetic variants underlying complex traits and diseases.
████░░░░░░4.52. pre-miRBench: a multispecies benchmark and reference model for animal precursor microRNA prediction
Motivation: Precursor microRNA (pre-miRNA) prediction is used to prioritize genomic hairpins for miRNA annotation.
████░░░░░░4.53. Linear Fitness Subspace in Protein Language Models Enables Sample-Efficient Directed Evolution
Model-guided directed evolution seeks to identify high-fitness protein variants under limited oracle budgets.
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More top stories
- arXivby Nieto-del-Amor, Fu, Muehlboeck +3
NeuroCBIR: A Fast and Accurate Image Retrieval System for Whole-Brain and Region-Specific MRI
Content-based image retrieval (CBIR) in neuroimaging enables the identification of structurally similar brain scans, supporting diagnosis, prognosis, and treatment planning; however, ....
No.04Verdict: NotableScore████░░░░░░4.5 - bioRxivby Luchner, Vorobieva, Makkar +6
Machine learning-assisted directed evolution yields dramatic improvement on novel AAV engineering task
Directed evolution enables the discovery of protein mutants with improved fitness through iterative rounds of selection and has been widely applied to adeno-associated virus (AAV) capsid ....
No.05Verdict: NotableScore████░░░░░░4.4 - arXivby Braun, Grant, Saxe
Not all solutions are created equal: An analytical dissociation of functional and representational similarity in deep linear neural networks
A foundational principle of connectionism is that perception, action, and cognition emerge from parallel computations among simple, interconnected units that generate and rely on neural ....
No.06Verdict: RoutineScore████░░░░░░4.4
Briefs
- Nature
Genome accessibility reveals disease risk that gene expression misses
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The Metabolic Organ Clock: A Computable Framework Linking Cell-Lineage Architecture to Emergent Organ Bioenergetics
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NeuroLens: Learning Latent Embeddings of Neural Semantics from Chronic Recordings
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Intraindividual longitudinal changes of the proteome reveal dynamic markers of biological aging
████░░░░░░4.3 - bioRxiv
Altered Aperiodic EEG Activity in Adolescents with Neurofibromatosis Type 1
████░░░░░░4.3 - bioRxiv
Branch-Wise Regularization for Heterogeneous GNN-Based MALDI-TOF AMR Prediction with Biomarker-Consensus Edges
████░░░░░░4.3 - bioRxiv
DigiFish: A flexible open-source tool for animating realistic virtual fish and reconstructing visual fields from tracking data
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Human FACT complex coordinates cohesin and transcription on chromatin
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