Genomes, cells, brains, and the tools that read and write them.
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bioRxiv
Verdict: NotableMost low-biomass disease-microbe associations measure biomass, not disease.
Human genetic variation is a powerful driver of therapeutic target prioritization, yet current models struggle to aggregate variable numbers of variants per gene and are bottlenecked by the scarcity of validated targets.
Antibody engineering campaigns must prioritise variants from large combinatorial libraries under limited assay budgets.
To bridge the gap between rapid RNA sequence discovery and slow experimental characterization, we present the NuFold RNA Structure Database (https://nufold.kiharalab.org/), a resource ....
Tetraspanins organize membrane domains that regulate inflammation.
Corals form intricate symbiotic relationships with diverse microbial communities that influence their physiology, evolution, and ecological function.
Revealing how distributed cortical circuits coordinate behavior in freely moving animals remains a central challenge in systems neuroscience, constrained by limited fields of view, low ....