bioRxiv
Verdict: NotableAn open-source, 3D-printable droplet microfluidics platform with strobe-enhanced microscopy
Droplet microfluidics underpins many single-cell, precision biomedical, and nanomaterial techniques.
Score█████░░░░░4.6
Biology
Genomes, cells, brains, and the tools that read and write them.
Edition No. 27
Updated UTC
Top stories
1. TRUEDA overturns replicated, decontaminated low-biomass disease-microbe associations and clinical decisions, recovers true pathogens and outperforms every decontamination method
Most low-biomass disease-microbe associations measure biomass, not disease.
Verdict: Notable█████░░░░░4.52. Population-scale drug target and variant prioritization with Varformer
Human genetic variation is a powerful driver of therapeutic target prioritization, yet current models struggle to aggregate variable numbers of variants per gene and are bottlenecked by the scarcity of validated targets.
Verdict: Notable████░░░░░░4.5
More top stories
- bioRxivby Chi
PROTFIG: one-command, publication-quality biomolecular figures
Molecular structures contain rich information about biomolecular interactions, but translating this information into clear, scientifically informative figures remains a largely manual ....
No.03Verdict: NotableScore████░░░░░░4.5 - bioRxivby Krishna, Singh, Srivastava +1
Active Learning framework for Antibody Binding Affinity Prediction
Antibody engineering campaigns must prioritise variants from large combinatorial libraries under limited assay budgets.
No.04Verdict: NotableScore████░░░░░░4.4 - Europe PMCby Ning, Zhou
Genome-wide detection of genotype-environment interactions at biobank scale with fastGxE
Traditional genome-wide association studies have primarily focused on detecting main genotype effects, often overlooking genotype-environment interactions (GxE), which are essential for ....
No.05Verdict: NotableScore████░░░░░░4.4 - bioRxivby Platt, Kagaya, Kihara
NuFold RNA Structure Database: Large-Scale RNA Tertiary Structure Prediction with Confidence Metrics
To bridge the gap between rapid RNA sequence discovery and slow experimental characterization, we present the NuFold RNA Structure Database (https://nufold.kiharalab.org/), a resource ....
No.06Verdict: NotableScore████░░░░░░4.3
Briefs
- bioRxiv
Tetraspanin changes in septic blood are organized by cell type, with monocyte CD82 induction and leukocyte CD37 loss associated with mortality
████░░░░░░4.3 - Nature
Cortex-wide imaging in naturally behaving mice with 1-gram wireless mesoscopes
████░░░░░░4.3 - bioRxiv
Open-source virtual reality platform for head-fixed adult zebrafish
████░░░░░░4.3 - bioRxiv
Global distribution and host specificity of plastid-bearing microeukaryotes across coral holobionts
████░░░░░░4.3 - Europe PMC
Lifestyle-induced regulatory T cell fragility primes adverse events after immune checkpoint blockade
████░░░░░░4.2 - bioRxiv
Integrating Multisource Target Evidence with Machine-Learning Potency Prediction for Alzheimer's Disease Drug Discovery
████░░░░░░4.2 - bioRxiv
A robust mutation spectrum analysis framework for high-depth error-corrected sequencing data
████░░░░░░4.2 - bioRxiv
Language models annotate mass cytometry clusters within the range where human experts disagree
████░░░░░░4.2